Dokument: Meningovascular Inflammation in Cerebral Amyloid Angiopathy‐Related Cortical Superficial Siderosis
| Titel: | Meningovascular Inflammation in Cerebral Amyloid Angiopathy‐Related Cortical Superficial Siderosis | |||||||
| URL für Lesezeichen: | https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=73544 | |||||||
| URN (NBN): | urn:nbn:de:hbz:061-20260610-104807-0 | |||||||
| Kollektion: | Publikationen | |||||||
| Sprache: | Englisch | |||||||
| Dokumententyp: | Wissenschaftliche Texte » Artikel, Aufsatz | |||||||
| Medientyp: | Text | |||||||
| Autoren: | Meuth, Sven [Autor] Arndt, Philipp [Autor] Khadhraoui, Eya [Autor] Müller, Sebastian J. [Autor] Neumann, Katja [Autor] Mattern, Hendrik [Autor] Perosa, Valentina [Autor] Charidimou, Andreas [Autor] Schreiber, Stefanie [Autor] | |||||||
| Dateien: |
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| Stichwörter: | inflammation , vessel wall imaging , cortical superficial siderosis , cerebral amyloid angiopathy | |||||||
| Beschreibung: | The role of inflammation in cortical superficial siderosis (cSS), a marker of cerebral amyloid angiopathy (CAA) linked to high hemorrhage risk, is unclear. We examined 15 patients with cSS using 3 T post-contrast vessel wall MRI (VWI) and CSF analysis. Although only 27% met current CAA-ri criteria, 93% showed vessel wall enhancement or sulcal hyperintensities near cSS, frequently extending beyond. Seven patients with follow-up VWI demonstrated corticosteroid-responsive regression of inflammation. CSF albumin quotients, indicating blood–brain barrier dysfunction, correlated with MRI inflammation scores. These findings reveal subclinical meningovascular inflammation in cSS and support VWI for detecting a broader CAA-related inflammation spectrum. | |||||||
| Rechtliche Vermerke: | Originalveröffentlichung:
Arndt, P., Khadhraoui, E., Müller, S. J., Neumann, K., Mattern, H., Meuth, S., Perosa, V., Charidimou, A., & Schreiber, S. (2026). Meningovascular Inflammation in Cerebral Amyloid Angiopathy‐Related Cortical Superficial Siderosis. Annals of Clinical and Translational Neurology, 13(5), 1052–1059. https://doi.org/10.1002/acn3.70315 | |||||||
| Lizenz: |  Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz | |||||||
| Fachbereich / Einrichtung: | Medizinische Fakultät | |||||||
| Dokument erstellt am: | 10.06.2026 | |||||||
| Dateien geändert am: | 10.06.2026 |
