Dokument: Motivations and experiences of high-risk men in risk-adapted prostate cancer early detection: A qualitative study

Titel:Motivations and experiences of high-risk men in risk-adapted prostate cancer early detection: A qualitative study
URL für Lesezeichen:https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=73111
URN (NBN):urn:nbn:de:hbz:061-20260429-115528-2
Kollektion:Publikationen
Sprache:Englisch
Dokumententyp:Wissenschaftliche Texte » Artikel, Aufsatz
Medientyp:Text
Autoren: Klett, Maike K. [Autor]
Balkan, Ilayda [Autor]
Lakes, Jale [Autor]
Albers, Peter [Autor]
Boschheidgen, Matthias [Autor]
Antoch, Gerald [Autor]
Redler, Silke [Autor]
Wieczorek, Dagmar [Autor]
Fehm, Tanja [Autor]
Jaeger, Bernadette Anna Sophia [Autor]
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Dateien vom 29.04.2026 / geändert 29.04.2026
Stichwörter:Prostate cancer , Early detection , Family history , Men's health , Genetic predisposition , Qualitative research , Genetic counselling
Beschreibung:Objective
Men with a family history of prostate cancer (PCa) or a pathogenic germline variant (PGV) face increased PCa risk. However, structured PCa early detection and insights into the experiences of affected men remain limited. This qualitative analysis explored (i) why men with familial or genetic PCa risk attended a risk-adapted prevention clinic, (ii) which elements they found helpful, and (iii) how early detection services could be tailored to their needs.
Methods
This study was part of the psychosocial mixed-methods study ProFam-Psych, run alongside the ProFam-Risk prevention clinic. Semi-structured interviews were conducted in a subgroup (13/86 study participants). The clinic offered PSA testing, mpMRI, genetic counselling and panel testing followed by risk-adapted recommendations. Participants were men without PCa who had a family history or previously detected PGV, and men with PCa who had a family history. Participants were selected using maximum variation sampling. Data were analysed by two researchers using Kuckartz’s qualitative content analysis.
Results
Seven motivators were identified: (1) clarify risk/PGV status, (2) information needs, (3) benefits for the family, (4) support others, (5) external recommendation, (6) access to structured screening, and (7) preventive recommendations. Participants with a family history were primarily motivated by (1) and (3), men with PGVs by (5) and (6), with (6) and (7) unique to this group. Perceptions of elements most helpful to participants varied, but the integrated setting with time for questions, clear guidance, and a reliable point of contact was valued. Suggested improvements were mostly organisational, including reminder systems to support long-term adherence.
Conclusion
Interdisciplinary early detection for PCa was accepted by participants, with motivators such as screening access and information needs highlighting the need for the implementation of structured screening programs for high-risk men.
Rechtliche Vermerke:Originalveröffentlichung:
Klett, Maike, Balkan, I., Lakes, J., Albers, P., Hiltrop, K., Rother, J., Boschheidgen, M., Antoch, G., Redler, S., Wieczorek, D., Fehm, T., Jäger, B. A. S., Dinger, U., & Karger, A. (2026). Motivations and experiences of high-risk men in risk-adapted prostate cancer early detection: A qualitative study. Patient Education and Counseling, 149, Article 109593. https://doi.org/10.1016/j.pec.2026.109593
Lizenz:Creative Commons Lizenzvertrag
Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz
Fachbereich / Einrichtung:Medizinische Fakultät
Dokument erstellt am:29.04.2026
Dateien geändert am:29.04.2026
english
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