Dokument: On age-specific selection and extensive lifespan beyond menopause
| Titel: | On age-specific selection and extensive lifespan beyond menopause | |||||||
| URL für Lesezeichen: | https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=71399 | |||||||
| URN (NBN): | urn:nbn:de:hbz:061-20251117-113653-5 | |||||||
| Kollektion: | Publikationen | |||||||
| Sprache: | Englisch | |||||||
| Dokumententyp: | Wissenschaftliche Texte » Artikel, Aufsatz | |||||||
| Medientyp: | Text | |||||||
| Autor: | Pang, Tin Yau [Autor] | |||||||
| Dateien: |
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| Stichwörter: | menopause , population genetics , kin selection , ageing | |||||||
| Beschreibung: | Standard evolutionary theory of ageing predicts weaker purifying selection on genes critical to later life stages. Prolonged postreproductive lifespan (PPRLS), observed only in a few species like humans, is likely a result of disparate relaxation of purifying selection on survival and reproduction in late life stages. While the exact origin of PPRLS is under debate, many researchers agree on hypotheses like mother-care and grandmother-care, which ascribe PPRLS to investment into future generations—provision to one’s descendants to enhance their overall reproductive success. Here, we simulate an agent-based model, which properly accounts for age-specific selection, to examine how different investment strategies affect the strength of purifying selection on survival and
reproduction. We observed in the simulations that investment strategies that allow a female individual to remain contributive to its own descendants (infants and adults) at late life stages may lead to differential relaxation of selection on survival and reproduction, and incur the adaptive evolution of PPRLS. | |||||||
| Rechtliche Vermerke: | Originalveröffentlichung:
Pang, T. Y. (2020). On age-specific selection and extensive lifespan beyond menopause [OnlineRessource]. Royal Society Open Science, 7, Article 191972. https://doi.org/10.1098/rsos.191972 | |||||||
| Lizenz: |  Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz | |||||||
| Fachbereich / Einrichtung: | Mathematisch- Naturwissenschaftliche Fakultät | |||||||
| Dokument erstellt am: | 17.11.2025 | |||||||
| Dateien geändert am: | 17.11.2025 |
