Dokument: Best practices for blood collection and anaesthesia in mice: Selection, application and reporting

Titel:Best practices for blood collection and anaesthesia in mice: Selection, application and reporting
URL für Lesezeichen:https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=69859
URN (NBN):urn:nbn:de:hbz:061-20250611-133239-9
Kollektion:Publikationen
Sprache:Englisch
Dokumententyp:Wissenschaftliche Texte » Artikel, Aufsatz
Medientyp:Text
Autoren: Li, Zhixin [Autor]
LoBue, Anthea [Autor]
Heuser, Sophia K. [Autor]
Li, Junjie [Autor]
Engelhardt, Eva [Autor]
Papapetropoulos, Andreas [Autor]
Patel, Hemal H. [Autor]
Lilley, Elliot [Autor]
Ferdinandy, Péter [Autor]
Schulz, Rainer [Autor]
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Dateien vom 11.06.2025 / geändert 11.06.2025
Stichwörter:reporting standards for mouse blood collection, mice anaesthesia and analgesia, refinement of blood sampling in mice, animal research regulations, mice blood collection, blood collection site in mice, microsampling, animal experiment reporting, mouse blood collection and welfare, anaesthetic protocols for mice, 3R principles, retro-orbital blood collection, animal experiment ethics, animal welfare guidelines, bleeding methods comparison
Beschreibung:Blood collection in mice is a common procedure in biomedical research. The choice of blood collection method and the need for analgesia and/or anaesthesia depend on multiple factors, including the experimental setup, animal welfare considerations and the intended downstream analyses. This minireview describes key non-surgical and surgical blood collection techniques, the appropriate use of analgesia and anaesthesia, and the best practice for documentation and adherence to reporting standards in animal studies. We here provide a table summarising collection procedures; a table listing animal welfare guidelines from multiple countries; a table describing the most common analgesics and anaesthetics, with doses and route of administration; and a table outlining key points for reporting blood collection, anaesthesia and analgesia protocols. A decision chart is also included to assist in selecting the most suitable method. Ultimately, with this minireview, we aim to promote standardised practices, improve data reproducibility, and support ethical animal research.
Rechtliche Vermerke:Originalveröffentlichung:
Li, Z., Lo Bue, A., Heuser, S. K., Li, J., Engelhardt, E., Papapetropoulos, A., Patel, H. H., Lilley, E., Ferdinandy, P., Schulz, R., & Cortese-Krott, M. M. (2025). Best practices for blood collection and anaesthesia in mice: Selection, application and reporting. British Journal of Pharmacology, 182(11), 2337–2353. https://doi.org/10.1111/bph.70029
Lizenz:Creative Commons Lizenzvertrag
Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz
Fachbereich / Einrichtung:Medizinische Fakultät
Dokument erstellt am:11.06.2025
Dateien geändert am:11.06.2025
english
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