Dokument: Best practices for blood collection and anaesthesia in mice: Selection, application and reporting
| Titel: | Best practices for blood collection and anaesthesia in mice: Selection, application and reporting | |||||||
| URL für Lesezeichen: | https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=69859 | |||||||
| URN (NBN): | urn:nbn:de:hbz:061-20250611-133239-9 | |||||||
| Kollektion: | Publikationen | |||||||
| Sprache: | Englisch | |||||||
| Dokumententyp: | Wissenschaftliche Texte » Artikel, Aufsatz | |||||||
| Medientyp: | Text | |||||||
| Autoren: | Li, Zhixin [Autor] LoBue, Anthea [Autor] Heuser, Sophia K. [Autor] Li, Junjie [Autor] Engelhardt, Eva [Autor] Papapetropoulos, Andreas [Autor] Patel, Hemal H. [Autor] Lilley, Elliot [Autor] Ferdinandy, Péter [Autor] Schulz, Rainer [Autor] | |||||||
| Dateien: |
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| Stichwörter: | reporting standards for mouse blood collection, mice anaesthesia and analgesia, refinement of blood sampling in mice, animal research regulations, mice blood collection, blood collection site in mice, microsampling, animal experiment reporting, mouse blood collection and welfare, anaesthetic protocols for mice, 3R principles, retro-orbital blood collection, animal experiment ethics, animal welfare guidelines, bleeding methods comparison | |||||||
| Beschreibung: | Blood collection in mice is a common procedure in biomedical research. The choice of blood collection method and the need for analgesia and/or anaesthesia depend on multiple factors, including the experimental setup, animal welfare considerations and the intended downstream analyses. This minireview describes key non-surgical and surgical blood collection techniques, the appropriate use of analgesia and anaesthesia, and the best practice for documentation and adherence to reporting standards in animal studies. We here provide a table summarising collection procedures; a table listing animal welfare guidelines from multiple countries; a table describing the most common analgesics and anaesthetics, with doses and route of administration; and a table outlining key points for reporting blood collection, anaesthesia and analgesia protocols. A decision chart is also included to assist in selecting the most suitable method. Ultimately, with this minireview, we aim to promote standardised practices, improve data reproducibility, and support ethical animal research. | |||||||
| Rechtliche Vermerke: | Originalveröffentlichung:
Li, Z., Lo Bue, A., Heuser, S. K., Li, J., Engelhardt, E., Papapetropoulos, A., Patel, H. H., Lilley, E., Ferdinandy, P., Schulz, R., & Cortese-Krott, M. M. (2025). Best practices for blood collection and anaesthesia in mice: Selection, application and reporting. British Journal of Pharmacology, 182(11), 2337–2353. https://doi.org/10.1111/bph.70029 | |||||||
| Lizenz: |  Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz | |||||||
| Fachbereich / Einrichtung: | Medizinische Fakultät | |||||||
| Dokument erstellt am: | 11.06.2025 | |||||||
| Dateien geändert am: | 11.06.2025 |
