Dokument: Associations of patient knowledge with drug-modifiable cardiovascular risk factor control in coronary artery disease patients with and without diabetes mellitus: results from the cross-sectional KNOW-ABC study
| Titel: | Associations of patient knowledge with drug-modifiable cardiovascular risk factor control in coronary artery disease patients with and without diabetes mellitus: results from the cross-sectional KNOW-ABC study | |||||||
| URL für Lesezeichen: | https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=69384 | |||||||
| URN (NBN): | urn:nbn:de:hbz:061-20250416-113153-2 | |||||||
| Kollektion: | Publikationen | |||||||
| Sprache: | Englisch | |||||||
| Dokumententyp: | Wissenschaftliche Texte » Artikel, Aufsatz | |||||||
| Medientyp: | Text | |||||||
| Autoren: | Brockmeyer, Maximilian [Autor] Fell, Michaela [Autor] Parco, Claudio [Autor] Hoss, Alexander [Autor] Vargas, Kris Gregory [Autor] Wies, Emilia [Autor] Lin, Yingfeng [Autor] Heinen, Yvonne [Autor] Chernyak, Nadja [Autor] Icks, Andrea [Autor] | |||||||
| Dateien: |
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| Stichwörter: | Patient information, Coronary artery disease, Treatment goals, Low-density lipoprotein cholesterol, Glycated hemoglobin, Patient knowledge, Blood pressure | |||||||
| Beschreibung: | Background
Control of major drug-modifiable risk factors for glycated hemoglobin (HbA1c), blood pressure (BP), and low-density lipoprotein cholesterol (LDL-C) remains unsatisfactory in the secondary prevention of coronary artery disease (CAD). We aimed to analyze patient knowledge and attainment of LDL-C, BP, and HbA1c treatment goals and associated factors in German CAD patients with and without diabetes mellitus (DM). Methods/Results A total of 204 CAD patients (68 ± 8 years; 75.0% male; 84 with DM (41.2%)) completed a questionnaire assessing their knowledge of LDL-C (< 55 mg/dL), BP (age-adapted), and HbA1c (< 7.0%) treatment goals and levels of information on predefined CAD topics as well as associated factors, including CAD duration, adherence to pharmacotherapy, and physician monitoring of secondary prevention. LDL-C, BP, and HbA1c were measured. The mean duration of CAD was 9.8 ± 8 years. A total of 98.5% reported good adherence to pharmacotherapy. Measurements of LDL-C (81.4%) and HbA1c (71.4%) were predominantly performed by general practitioners. LDL-C goals were attained significantly better in patients with DM (39.3% with vs. 16.7% without DM, p < 0.01). The attainment of BP goals did not differ between patients with and without DM (71.4% vs. 72.5%, p = 0.87). HbA1c goals were attained by 48.8% of DM patients. LDL-C goals were known by 6.0% of patients with vs. 9.2% without DM (p = 0.44), and BP goals were known by 36.9% with vs. 30.0% without DM (p = 0.36). Knowledge of HbA1c goals was prevalent in 53.6% of DM patients. Subjective levels of information on CAD topics did not differ between patients with and without DM. Logistic regression revealed that DM (odds ratio (OR) 3.73, 95% confidence interval (CI) 1.82–7.63) and knowledge of treatment goals were associated with LDL-C goal attainment (OR 3.84, CI 1.19–12.41); no such associations were identified for BP or HbA1c. Conclusions In German CAD patients with and without DM, a remarkable lack of knowledge and attainment of LDL-C treatment goals exists compared with BP and HbA1c. DM and knowledge of treatment goals were significantly associated with LDL-C treatment goal attainment. General practitioners rather than cardiologists or other specialties currently manage risk factor control. | |||||||
| Rechtliche Vermerke: | Originalveröffentlichung:
Brockmeyer, M., Fell, M., Parco, C., Hoss, A., Vargas, K. G., Wies, E., Lin, Y., Heinen, Y., Chernyak, N., Icks, A., Jung, C., Kelm, M., & Wolff, G. (2025). Associations of patient knowledge with drug-modifiable cardiovascular risk factor control in coronary artery disease patients with and without diabetes mellitus: results from the cross-sectional KNOW-ABC study. BMC Cardiovascular Disorders, 25, Article 148. https://doi.org/10.1186/s12872-025-04599-7 | |||||||
| Lizenz: |  Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz | |||||||
| Fachbereich / Einrichtung: | Medizinische Fakultät | |||||||
| Dokument erstellt am: | 16.04.2025 | |||||||
| Dateien geändert am: | 16.04.2025 |
