Dokument: Genicular Artery Embolization in Moderate to Severe Knee Osteoarthritis: Technique, Safety and Clinical Outcome
| Titel: | Genicular Artery Embolization in Moderate to Severe Knee Osteoarthritis: Technique, Safety and Clinical Outcome | |||||||
| URL für Lesezeichen: | https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=69314 | |||||||
| URN (NBN): | urn:nbn:de:hbz:061-20250411-120343-3 | |||||||
| Kollektion: | Publikationen | |||||||
| Sprache: | Englisch | |||||||
| Dokumententyp: | Wissenschaftliche Texte » Artikel, Aufsatz | |||||||
| Medientyp: | Text | |||||||
| Autoren: | Taheri Amin, Arian [Autor] Frommhold, I. [Autor] Huebner, Anne [Autor] Boschheidgen, Matthias [Autor] Frenken, Miriam [Autor] Jannusch, Kai [Autor] Tietz, Eric [Autor] Weiss, Daniel Arvid [Autor] Wilms, Lena M. [Autor] Ziayee, Farid [Autor] | |||||||
| Dateien: |
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| Stichwörter: | Clinical outcome, Technique, Vascular complications, Genicular artery embolization, Radiation exposure, Safety | |||||||
| Beschreibung: | Purpose
To evaluate the safety and clinical outcomes of genicular artery embolization for knee osteoarthritis (OA). Materials and Methods A total of 43 patients suffering from osteoarthritis of the knee (Kellgren and Lawrence grades 2–4) were included in this prospective study. Peri-interventional data including vascular access, embolized target vessels, fluoroscopy time and radiation dose were collected. After 2-, 3- and 12-month pain scores, functional outcomes and adverse events were assessed through a standardized questionnaire. Results All embolizations were performed via a coaxial system consisting of a 4F Cobra catheter and a Microcatheter without the use of an introducer sheath. A mixture of contrast agent (Accupaque, GE, USA) and microspheres (Embosphere, Merit Medical, USA) was injected. At least three genicular branches were embolized per patient with following incidence: inferior lateral genicular artery (77%), superior lateral genicular artery (74%) and descending genicular artery (74%). The mean total volume of permanent embolic agent used was 3.6 ± 1.3 ml. The average fluoroscopy time was 29 ± 11 min, and radiation dose was 40.84 ± 26.21 Gy/cm2. During the 1-year follow-up, patients pain while walking showed an average reduction of 2.0 ± 0.5 points on the numeric rating scale (p < 0.0001), without any significant difference between different grades of osteoarthritis. Besides mild transient skin discolorations in four patients, no complications were observed. Conclusion Embolization of multiple genicular artery branches in a single session using microspheres in averaged doses higher than 2 ml total is safe and effective in reducing pain and improving functionality in patients with symptomatic OA, regardless of severity grade. | |||||||
| Rechtliche Vermerke: | Originalveröffentlichung:
Taheri Amin, A., Frommhold, I., Hübner, A., Boschheidgen, M., Frenken, M., Jannusch, K., Tietz, E., Weiß, D. A., Wilms, L. M., Ziayee, F., & Minko, P. (2025). Genicular Artery Embolization in Moderate to Severe Knee Osteoarthritis: Technique, Safety and Clinical Outcome. CardioVascular and Interventional Radiology, 48(3), 340–350. https://doi.org/10.1007/s00270-025-03983-2 | |||||||
| Lizenz: |  Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz | |||||||
| Fachbereich / Einrichtung: | Medizinische Fakultät | |||||||
| Dokument erstellt am: | 11.04.2025 | |||||||
| Dateien geändert am: | 11.04.2025 |
