Dokument: The influence of sintering of osteoporotic vertebral fractures on the sagittal lumbar profile and degenerative changes

Titel:The influence of sintering of osteoporotic vertebral fractures on the sagittal lumbar profile and degenerative changes
URL für Lesezeichen:https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=69287
URN (NBN):urn:nbn:de:hbz:061-20250410-113137-5
Kollektion:Publikationen
Sprache:Englisch
Dokumententyp:Wissenschaftliche Texte » Artikel, Aufsatz
Medientyp:Text
Autoren: Beyersdorf, Christoph [Autor]
Prost, Max [Autor]
Röckner, Melanie Elisabeth [Autor]
Maus, Uwe Martin [Autor]
Jacobs, Cornelius [Autor]
Scheyerer, Max Joseph [Autor]
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Dateien vom 10.04.2025 / geändert 10.04.2025
Stichwörter:Spinal stenosis, Spinal surgery, Osteoporosis, Vertebral body fracture, Degenerative spine disease
Beschreibung:Background

Osteoporosis, a skeletal disorder affecting nearly 20% of the global population, poses a significant health concern, with osteoporotic vertebral body fractures (VBF) representing a common clinical manifestation. The impact of osteoporotic sintering fractures in the thoracolumbar spine on the sagittal lumbar profile is incompletely understood and may lead to the onset of clinical symptoms in previously asymptomatic patients.
Methods

This retrospective single-center study analyzed data from patients presenting with osteoporotic spine fractures between 2017 and 2022. Patient selection involved stringent inclusion and exclusion criteria, focusing on radiologically documented osteoporotic sintering fractures in the thoracolumbar junction (TH11-L2). Clinical parameters were recorded and analyzed, alongside lateral-view radiographic assessments utilizing the IDS 7-PACS®-System (Sectra, Linköping, Sweden). Measurements included total lumbar lordosis, lordosis caudal to the fracture, kyphosis of the fractured vertebra, and sacral slope. Statistical analysis was conducted using SPSS 27 (IBM, Armonk, USA).
Results

Thirty patients (73.3% female, 26.7% male) met the inclusion criteria, with an average age of 82.4 years. Analysis revealed a significant increase in kyphosis of the fractured vertebra in the thoracolumbar spine (p < 0.0001) following further sintering of osteoporotic VBF with increased lordosis caudal to the fracture (p < 0.0001). Total lumbar lordosis remained unchanged, alongside sacral slope measurements (p = 0.612 and p = 0.863, respectively).
Conclusion

Progressive sintering of osteoporotic fractures in the thoracolumbar junction accentuates lordosis in underlying segments, potentially exacerbating degenerative changes and symptomatic manifestations. Thus, prioritizing interventions aimed at preventing progressive sintering and restoring sagittal balance is paramount in optimizing treatment outcomes for affected individuals.
Rechtliche Vermerke:Originalveröffentlichung:
Beyersdorf, C. C. P., Prost, M., Röckner, M. E., Maus, U., Jacobs, C., & Scheyerer, M. J. (2025). The influence of sintering of osteoporotic vertebral fractures on the sagittal lumbar profile and degenerative changes. Journal of Orthopaedic Surgery and Research, 20, Article 23. https://doi.org/10.1186/s13018-025-05454-3
Lizenz:Creative Commons Lizenzvertrag
Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz
Fachbereich / Einrichtung:Medizinische Fakultät
Dokument erstellt am:10.04.2025
Dateien geändert am:10.04.2025
english
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