Dokument: Oxytocin effects on socially transmitted food preferences are moderated by familiarity between rats
| Titel: | Oxytocin effects on socially transmitted food preferences are moderated by familiarity between rats | |||||||
| URL für Lesezeichen: | https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=68992 | |||||||
| URN (NBN): | urn:nbn:de:hbz:061-20250311-130533-9 | |||||||
| Kollektion: | Publikationen | |||||||
| Sprache: | Englisch | |||||||
| Dokumententyp: | Wissenschaftliche Texte » Artikel, Aufsatz | |||||||
| Medientyp: | Text | |||||||
| Autoren: | Noguer-Calabús, Irina [Autor] Schäble, Sandra [Autor] Dören, José [Autor] Kalenscher, Tobias [Autor] | |||||||
| Dateien: |
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| Stichwörter: | Food preference, Social behavior, Oxytocin, Reward revaluation, Familiarity, Group bias | |||||||
| Beschreibung: | Rationale
In the socially transmitted food preference (STFP) paradigm, rats change their preference for food rewards after socially interacting with a conspecific who has been fed with the originally non-preferred food. Here, we asked if oxytocin (OXT), a neuropeptide known for its role in social affiliation and social behavior, plays a role in STFP. Since OXT’s influences on social behavior can be familiarity-dependent, we further asked if OXT effects on STFP are moderated by the familiarity between rats. Objectives Does OXT modulate rats’ socially transmitted food choices in a familiarity-dependent way. Methods We systemically injected either vehicle, low-dose (0.25 mg/kg) of OXT, or large-dose (1.0 mg/kg) of OXT before social interaction with either a familiar cagemate (in-group) or an unfamiliar conspecific from a different cage (out-group). Results We found an intergroup bias in STFP: vehicle-treated rats showed larger socially transmitted changes in food preference in the out-group than the in-group condition. OXT modulated STFP in a familiarity-dependent way: OXT prevented the increase in the consumption of the non-preferred food in the out-group, and decreased the consumption of the preferred food in the in-group. These effects were dose-dependent and observed under acute OXT action, but also on the subsequent day when acute OXT effects dissipated, suggesting long-lasting social learning effects of OXT. Additional analyses suggest that the familiarity and dose-dependent effects of OXT on STFP cannot be attributed to OXT’s anorexic actions or differences in the duration of the social interactions. Conclusions OXT modulates STFP in a familiarity-dependent way. | |||||||
| Rechtliche Vermerke: | Originalveröffentlichung:
Calabús, I., Schäble, S., Dören, J. M., & Kalenscher, T. (2024). Oxytocin effects on socially transmitted food preferences are moderated by familiarity between rats. Psychopharmacology, 242(2), 361–372. https://doi.org/10.1007/s00213-024-06682-x | |||||||
| Lizenz: |  Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz | |||||||
| Fachbereich / Einrichtung: | Mathematisch- Naturwissenschaftliche Fakultät | |||||||
| Dokument erstellt am: | 11.03.2025 | |||||||
| Dateien geändert am: | 11.03.2025 |
