Dokument: Cerebral perfusion changes in acute subdural hematoma
| Titel: | Cerebral perfusion changes in acute subdural hematoma | |||||||
| URL für Lesezeichen: | https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=68741 | |||||||
| URN (NBN): | urn:nbn:de:hbz:061-20250221-094632-4 | |||||||
| Kollektion: | Publikationen | |||||||
| Sprache: | Englisch | |||||||
| Dokumententyp: | Wissenschaftliche Texte » Artikel, Aufsatz | |||||||
| Medientyp: | Text | |||||||
| Autoren: | Winkler, Jennifer [Autor] Santos Piedade, Guilherme [Autor] Rubbert, Christian [Autor] Hofmann, Björn Bastian [Autor] Kamp, M.A. [Autor] Slotty, Philipp Jörg [Autor] | |||||||
| Dateien: |
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| Stichwörter: | CT perfusion, Traumatic brain injury, Acute subdural hematoma, Cerebral perfusion | |||||||
| Beschreibung: | Introduction
Acute subdural hematoma (aSDH) is one of the main causes of high mortality and morbidity in traumatic brain injury. Prognosis is poor due to the rapid volume shift and mass effect. Cerebral perfusion is likely affected in this condition. This study quantifies perfusion changes in aSDH using early ER polytrauma CT with perfusion imaging (CTP). Methods Data of 54 patients with traumatic aSDH were retrospectively collected. Glasgow Coma scale (GCS), perfusion parameters, therapeutic decisions and imaging data including hematoma thickness, midline shift, and hematoma localization were analyzed. The cortical perfusion parameters of each hemisphere, the area anterior to the hematoma (AAH), area below the hematoma (ABH), area posterior to the hematoma (PAH), and corresponding mirrored contralateral regions were determined. Results We found a significant difference in Tmax in affected and unaffected whole-hemisphere data (mean 4.0 s vs. 3.3 s, p < 0.05) and a significantly different mean for Tmax in ABH and for the corresponding mirrored area (mABH) (mean 3.8 s vs. 3.1 s, p < 0.05). No significant perfusion changes in cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT) were found. Conclusion There was a significant elevation of time to maximum (Tmax) values in the underlying cortical area of aSDH. Possible pathophysiological explanations, the influence on immediate surgical decision-making and further therapeutic consequences have to be evaluated. | |||||||
| Rechtliche Vermerke: | Originalveröffentlichung:
Winkler, J., Santos Piedade, G., Rubbert, C., Hofmann, B. B., Kamp, M. A., & Slotty, P. J. (2023). Cerebral perfusion changes in acute subdural hematoma. Acta Neurochirurgica, 165(9), 2381–2387. https://doi.org/10.1007/s00701-023-05703-6 | |||||||
| Lizenz: |  Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz | |||||||
| Fachbereich / Einrichtung: | Medizinische Fakultät | |||||||
| Dokument erstellt am: | 21.02.2025 | |||||||
| Dateien geändert am: | 21.02.2025 |
