Dokument: The Association between Aortic Valve Stenosis and a Subsequent Diagnosis of Depression in Germany
| Titel: | The Association between Aortic Valve Stenosis and a Subsequent Diagnosis of Depression in Germany | |||||||
| URL für Lesezeichen: | https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=68533 | |||||||
| URN (NBN): | urn:nbn:de:hbz:061-20250210-091108-8 | |||||||
| Kollektion: | Publikationen | |||||||
| Sprache: | Englisch | |||||||
| Dokumententyp: | Wissenschaftliche Texte » Artikel, Aufsatz | |||||||
| Medientyp: | Text | |||||||
| Autoren: | Niepmann, Sven Thomas [Autor] Roderburg, Christoph [Autor] Luedde, Mark [Autor] Nickenig, Georg [Autor] Loosen, Sven H. [Autor] Kostev, Karel [Autor] | |||||||
| Dateien: |
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| Stichwörter: | cardiovascular disease, aortic valve stenosis, depression, mood disorders, epidemiology | |||||||
| Beschreibung: | Background/Objectives: Aortic valve stenosis (AS) represents one of the most common valve diseases in the western world. It often leads to severe symptoms that can lead to a restriction of everyday life and thus to psychological stress. Therefore, we aimed to investigate the association between AS and depression in outpatients in Germany.
Methods: The IQVIATM Disease Analyzer database was used to identify 14,681 individuals with non-rheumatic AS (ICD-10: I35.0 or I35.2). They were propensity score matched (1:1) based on age, sex, average yearly consultation frequency during the follow-up, and co-diagnoses to 14,681 patients without AS. Cox regression models were used to analyze the association between aortic stenosis and depression. Results: Within the follow-up period of up to 10 years, depression was diagnosed in 20.6% of AS patients compared to 20.0% in the matched cohort (p = 0.351). In the regression analysis, we were not able to discover an association between AS and a subsequent diagnosis of depression (HR: 1.03; 95% CI: 0.96–1.11). This effect was consistent among different age and sex groups. Conclusions: In the broad population of patients treated outside of hospital settings in Germany, AS was not associated with a higher incidence of depression. | |||||||
| Rechtliche Vermerke: | Originalveröffentlichung:
Niepmann, S. T., Roderburg, C., Luedde, M., Nickenig, G., Loosen, S. H., & Kostev, K. (2024). The Association between Aortic Valve Stenosis and a Subsequent Diagnosis of Depression in Germany. Journal of Clinical Medicine, 13(18), Article 5525. https://doi.org/10.3390/jcm13185525 | |||||||
| Lizenz: |  Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz | |||||||
| Fachbereich / Einrichtung: | Medizinische Fakultät | |||||||
| Dokument erstellt am: | 10.02.2025 | |||||||
| Dateien geändert am: | 10.02.2025 |
