Dokument: Questionnaire Study to Investigate the Preferences of Children, Parents, and Healthcare Professionals for Different Formulations of Oral Medicinal Products

Titel:Questionnaire Study to Investigate the Preferences of Children, Parents, and Healthcare Professionals for Different Formulations of Oral Medicinal Products
URL für Lesezeichen:https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=68376
URN (NBN):urn:nbn:de:hbz:061-20250131-095352-4
Kollektion:Publikationen
Sprache:Englisch
Dokumententyp:Wissenschaftliche Texte » Artikel, Aufsatz
Medientyp:Text
Autoren: Wargenau, Manfred [Autor]
Baase, Felicitas [Autor]
Eckhardt, Kristin [Autor]
Spitzhorn, Lucas-Sebastian [Autor]
Reidemeister, Sibylle [Autor]
Klingmann, Ingrid [Autor]
Klingmann, Viviane [Autor]
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Dateien vom 31.01.2025 / geändert 31.01.2025
Stichwörter:mini-tablets, medicinal product administration, medicine dosage form, pediatric formulation
Beschreibung:Since the acceptability of a medicine can significantly impact therapeutic outcomes, this study aimed to determine and compare the preferences of children, parents, and healthcare professionals for the most commonly used pediatric oral medicine formulations (syrup, mini-tablets, oblong tablets, round tablets) addressing all pediatric age groups, 0–<18 years (y). This survey study employed sex-, age-, and participant group-adapted questionnaires for eight cohorts of participants, i.e., children 6–<12 y, adolescents 12–<18 y, parents of children in four age groups (0–<2 y, 2–<6 y, 6–<12 y, and 12–<18 y), nurses, and pediatricians. Descriptive statistics were used for data analysis. In the age groups 0–<2 y and 2–<6 y, mini-tablets were preferred over syrup by all participants. In the age group 6–12 y, solid dosage forms were also preferred over syrup by all participants. In the age group 12–<18 y, healthcare professionals preferred solid dosage forms over syrup. Parents preferred higher amounts of mini-tablets and syrup compared to round and oblong tablets, while adolescents’ preferences did not differentiate between these formulations. Based on the study results and in contrast to current practice, it is suggested to consider solid dosage forms for future age-appropriate medicinal products already for younger age groups.
Rechtliche Vermerke:Originalveröffentlichung:
Wargenau, M., Baase, F., Eckardt, K., Spitzhorn, L.-S., Reidemeister, S., Klingmann, I., & Klingmann, V. (2024). Questionnaire Study to Investigate the Preferences of Children, Parents, and Healthcare Professionals for Different Formulations of Oral Medicinal Products. Pharmaceutics, 16(4), Article 515. https://doi.org/10.3390/pharmaceutics16040515
Lizenz:Creative Commons Lizenzvertrag
Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz
Fachbereich / Einrichtung:Medizinische Fakultät
Dokument erstellt am:31.01.2025
Dateien geändert am:31.01.2025
english
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