Dokument: Exploring the electrophysiology of Parkinson’s disease with magnetoencephalography and deep brain recordings

Titel:Exploring the electrophysiology of Parkinson’s disease with magnetoencephalography and deep brain recordings
URL für Lesezeichen:https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=68311
URN (NBN):urn:nbn:de:hbz:061-20250128-084257-8
Kollektion:Publikationen
Sprache:Englisch
Dokumententyp:Wissenschaftliche Texte » Artikel, Aufsatz
Medientyp:Text
Autoren: Rassoulou, Fayed [Autor]
Steina, Alexandra [Autor]
Hartmann, Christian Johannes [Autor]
Vesper, Jan [Autor]
Butz, Markus [Autor]
Schnitzler, Alfons [Autor]
Hirschmann, Jan [Autor]
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Dateien vom 28.01.2025 / geändert 28.01.2025
Beschreibung:Aberrant information processing in the basal ganglia and connected cortical areas are key to many neurological movement disorders such as Parkinson’s disease. Investigating the electrophysiology of this system is difficult in humans because non-invasive methods, such as electroencephalography or magnetoencephalography, have limited sensitivity to deep brain areas. Recordings from electrodes implanted for therapeutic deep brain stimulation, in contrast, provide clear deep brain signals but are not suited for studying cortical activity. Therefore, we combine magnetoencephalography and local field potential recordings from deep brain stimulation electrodes in individuals with Parkinson’s disease. Here, we make these data available, inviting a broader scientific community to explore the dynamics of neural activity in the subthalamic nucleus and its functional connectivity to cortex. The dataset encompasses resting-state recordings, plus two motor tasks: static forearm extension and self-paced repetitive fist clenching. Most patients were recorded both in the medicated and the unmedicated state. Along with the raw data, we provide metadata on channels, events and scripts for pre-processing to help interested researchers get started.
Rechtliche Vermerke:Originalveröffentlichung:
Rassoulou, F., Steina, A., Hartmann, C., Vesper, J., Butz, M., Schnitzler, A., & Hirschmann, J. (2024). Exploring the electrophysiology of Parkinson’s disease with magnetoencephalography and deep brain recordings. Scientific Data, 11, Article 889. https://doi.org/10.1038/s41597-024-03768-1
Lizenz:Creative Commons Lizenzvertrag
Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz
Fachbereich / Einrichtung:Medizinische Fakultät
Dokument erstellt am:28.01.2025
Dateien geändert am:28.01.2025
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