Dokument: Perioperative antibiotic prophylaxis in the setting of cochlear implantation: a retrospective analysis of 700 cases

Titel:Perioperative antibiotic prophylaxis in the setting of cochlear implantation: a retrospective analysis of 700 cases
URL für Lesezeichen:https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=68105
URN (NBN):urn:nbn:de:hbz:061-20250113-110014-6
Kollektion:Publikationen
Sprache:Englisch
Dokumententyp:Wissenschaftliche Texte » Artikel, Aufsatz
Medientyp:Text
Autoren: Schaumann, Katharina [Autor]
Mütz, David [Autor]
Althaus, Laurenz [Autor]
Prinzen, Tom [Autor]
Schipper, Jörg [Autor]
Klenzner, Thomas [Autor]
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Dateien vom 13.01.2025 / geändert 13.01.2025
Stichwörter:Cochlear implantation, Wound infection, Revision surgery, Perioperative antibiotic prophylaxis, Surgical site infection, Explantation
Beschreibung:Purpose

Postoperative wound infections after cochlear implantation are rare but sometimes serious and can lead to explantation. Therefore, perioperative antibiotic administration is often recommended. However, in clinical practice, the type and duration of antibiotic prophylaxis varies between different centers. The aim of this study was to investigate the role of perioperative antibiotic prophylaxis in preventing postoperative complications.
Methods

700 patients who underwent cochlear implantation between 2007 and 2019 were retrospectively evaluated with regard to wound infections within the first 28 postoperative days. These were classified into major and minor complications. Data were analyzed using the IBM statistical program SPSS.
Results

In 670 out of 700 patients the type and duration of perioperative antibiotic administration could be reconstructed from the records. Of these 67 patients (10%) received antibiotics as a single shot, 158 patients (23.6%) were treated with antibiotics for a period of 48 h, and 445 patients (66.4%) received prolonged antibiotic therapy for more than 72 h. In total 64 patients (9.5%) showed abnormalities in wound assessment within the first 28 postoperative days after implantation. Major infections (1.6%) were detected in 11 patients. Overall, there was no statistically significant difference in wound infection rates between the group receiving single-shot antibiosis and the group receiving 48 h prophylaxis or antibiotic treatment > 72 h (p = 0.46).
Conclusion

Patients receiving an antibiotic single shot do not appear to be at significantly increased risk for postoperative wound infections compared with patients with prolonged antibiotic treatment. Continuation of data collection across centers seems reasonable.
Rechtliche Vermerke:Originalveröffentlichung:
Schaumann, K., Mütz, D., Althaus, L., Prinzen, T., Schipper , J., & Klenzner, T. (2024). Perioperative antibiotic prophylaxis in the setting of cochlear implantation: a retrospective analysis of 700 cases. European Archives of Oto-Rhino-Laryngology and Head & Neck, 281(8), 4021–4028. https://doi.org/10.1007/s00405-024-08515-1
Lizenz:Creative Commons Lizenzvertrag
Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz
Fachbereich / Einrichtung:Medizinische Fakultät
Dokument erstellt am:13.01.2025
Dateien geändert am:13.01.2025
english
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