Dokument: Review of current treatment modalities and clinical outcome of giant saccular aneurysms of the basilar apex
| Titel: | Review of current treatment modalities and clinical outcome of giant saccular aneurysms of the basilar apex | |||||||
| URL für Lesezeichen: | https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=68074 | |||||||
| URN (NBN): | urn:nbn:de:hbz:061-20250109-105700-2 | |||||||
| Kollektion: | Publikationen | |||||||
| Sprache: | Englisch | |||||||
| Dokumententyp: | Wissenschaftliche Texte » Artikel, Aufsatz | |||||||
| Medientyp: | Text | |||||||
| Autoren: | Theofanopoulos, Andreas [Autor] Troude, Lucas [Autor] Neyazi, Milad [Autor] Muhammad, Sajjad [Autor] | |||||||
| Dateien: |
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| Stichwörter: | Outcome Endovascular treatment Giant basilar aneurysm Surgical treatment Saccular aneurysm | |||||||
| Beschreibung: | Introduction
Giant aneurysms of the basilar apex represent formidable challenges as the high rupture rate of untreated lesions must be balanced against the technical complexity and potential morbidity of intervention. Research question Review of treatment modalities and outcomes of patients harboring giant (>2.5 cm) basilar apex saccular aneurysms, in an effort to refine treatment decision-making. Material and methods A systematic literature review through the PubMed and Scopus databases was performed according to the PRISMA guidelines to identify cases of giant basilar apex saccular aneurysms treated either microsurgically or endovascularly. Patients’ demographics, aneurysm size, preoperative and postoperative neurologic status, angiographic and clinical outcomes as well as follow-up information were obtained. Results Data from 32 studies fulfilling the inclusion criteria, including 49 patients (32 treated surgically and 17 endovascularly) was obtained. Mean patient age at presentation was 51.69 years, with a male-to-female ratio of 1:2. Mean maximum aneurysm diameter was 30.57 mm. A favorable outcome (mRS 0–2) was reported on 70.6% of endovascular and 56.3% of open surgical cases. Complete aneurysm occlusion was achieved in 55.6% of the open and 23.5% of the endovascular cases. Death rate was 33% for endovascular and 15.6% for open cases; the higher mortality of endovascular treatment is mainly attributed to the mass effect from continued brainstem compression after treatment. Discussion and conclusion Higher rates of complete occlusion but higher morbidity are associated with microsurgery compared to endovascular modalities. Severe, clinically apparent brainstem mass effect may require decompression associated with microsurgery, when technically feasible. | |||||||
| Rechtliche Vermerke: | Originalveröffentlichung:
Theofanopoulos, A., Troude, L., Neyazi, M., & Muhammad, S. (2024). Review of current treatment modalities and clinical outcome of giant saccular aneurysms of the basilar apex. Brain and Spine, 4, Article 103333. https://doi.org/10.1016/j.bas.2024.103333 | |||||||
| Lizenz: |  Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz | |||||||
| Fachbereich / Einrichtung: | Medizinische Fakultät | |||||||
| Dokument erstellt am: | 09.01.2025 | |||||||
| Dateien geändert am: | 09.01.2025 |
