Dokument: Evaluation of FRESH scores in predicting outcome and quality of life after aneurysmal subarachnoid haemorrhage in a European patient cohort

Titel:Evaluation of FRESH scores in predicting outcome and quality of life after aneurysmal subarachnoid haemorrhage in a European patient cohort
URL für Lesezeichen:https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=68010
URN (NBN):urn:nbn:de:hbz:061-20241219-124409-5
Kollektion:Publikationen
Sprache:Englisch
Dokumententyp:Wissenschaftliche Texte » Artikel, Aufsatz
Medientyp:Text
Autoren: Hofmann, Björn B. [Autor]
Gundlach, Evgenia P. [Autor]
Fischer, Igor [Autor]
Muhammad, Sajjad [Autor]
Kram, Rainer [Autor]
Beseoglu, Kerim [Autor]
Cornelius, Jan Frederick [Autor]
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Dateien vom 19.12.2024 / geändert 19.12.2024
Stichwörter:Patient-reported outcome, Quality of life (QoL), SF-36, Aneurysmal subarachnoid haemorrhage
Beschreibung:Background

Despite aneurysmal subarachnoid haemorrhage (aSAH) patients often experiencing physical and mental disabilities impacting their quality of life (QoL), routine assessment of long-term QoL data and predictive tools are limited. This study evaluates the newly developed “functional recovery expected after subarachnoid haemorrhage” (FRESH) scores with long-term outcomes and QoL in European aSAH patients.
Methods

FRESH, FRESH-cog, and FRESH-quol scores were retrospectively obtained from aSAH patients. Patients were contacted, and the modified Rankin Scale (mRS), extended short form-36 (SF-36), and telephone interview for cognitive status (TICS) were collected and performed. The prognostic and empirical outcomes were compared.
Results

Out of 374 patients, 171 patients (54.1%) completed the SF-36, and 154 patients completed the TICS. The SF-36 analysis showed that 32.7% had below-average physical component summary (PCS) scores, and 39.8% had below-average mental component summary (MCS) scores. There was no significant correlation between the FRESH score and PCS (p = 0.09736), MCS (p = 0.1796), TICS (p = 0.7484), or mRS 10–82 months (average 46 months) post bleeding (p = 0.024), respectively. There was also no significant correlation found for “FRESH-cog vs. TICS” (p = 0.0311), “FRESH-quol vs. PCS” (p = 0.0204), “FRESH-quol vs. MCS” (p = 0.1361) and “FRESH-quol vs. TICS” (p = 0.1608).
Conclusions

This study found no correlation between FRESH scores and validated QoL tools in a European population of aSAH patients. The study highlights the complexity of reliable long-term QoL prognostication in aSAH patients and emphasises the need for further prospective research to also focus on QoL as an important outcome parameter.
Rechtliche Vermerke:Originalveröffentlichung:
Hofmann, B. B., Gundlach, E. P., Fischer, I., Muhammad, S., Kram, R., Beseoglu, K., & Cornelius, J. F. (2024). Evaluation of FRESH scores in predicting outcome and quality of life after aneurysmal subarachnoid haemorrhage in a European patient cohort. Acta Neurochirurgica, 166(1), Article 29. https://doi.org/10.1007/s00701-024-05909-2
Lizenz:Creative Commons Lizenzvertrag
Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz
Fachbereich / Einrichtung:Medizinische Fakultät
Dokument erstellt am:19.12.2024
Dateien geändert am:19.12.2024
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