Dokument: Haplotype-resolved assembly of a tetraploid potato genome using long reads and low-depth offspring data
| Titel: | Haplotype-resolved assembly of a tetraploid potato genome using long reads and low-depth offspring data | |||||||
| URL für Lesezeichen: | https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=68005 | |||||||
| URN (NBN): | urn:nbn:de:hbz:061-20241219-111234-8 | |||||||
| Kollektion: | Publikationen | |||||||
| Sprache: | Englisch | |||||||
| Dokumententyp: | Wissenschaftliche Texte » Artikel, Aufsatz | |||||||
| Medientyp: | Text | |||||||
| Autoren: | Serra Mari, Rebecca [Autor] Schrinner, Sven [Autor] Finkers, Richard [Autor] Ziegler, Freya Maria Rosemarie [Autor] Arens, Paul [Autor] Schmidt, Maximilian H.-W. [Autor] Usadel, Björn [Autor] Klau, Gunnar W. [Autor] Marschall, Tobias [Autor] | |||||||
| Dateien: |
| |||||||
| Beschreibung: | Potato is one of the world’s major staple crops, and like many important crop plants, it has a polyploid genome. Polyploid haplotype assembly poses a major computational challenge. We introduce a novel strategy for the assembly of polyploid genomes and present an assembly of the autotetraploid potato cultivar Altus. Our method uses low-depth sequencing data from an offspring population to achieve chromosomal clustering and haplotype phasing on the assembly graph. Our approach generates high-quality assemblies of individual chromosomes with haplotype-specific sequence resolution of whole chromosome arms and can be applied in common breeding scenarios where collections of offspring are available. | |||||||
| Rechtliche Vermerke: | Originalveröffentlichung:
Serra Mari, R., Schrinner, S., Finkers, R., Ziegler, F. M. R., Arens, P., Schmidt, M. H.-W., Usadel, B., Klau, G., & Marschall, T. (2024). Haplotype-resolved assembly of a tetraploid potato genome using long reads and low-depth offspring data. Genome Biology, 25, Article 26. https://doi.org/10.1186/s13059-023-03160-z | |||||||
| Lizenz: |  Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz | |||||||
| Fachbereich / Einrichtung: | Mathematisch- Naturwissenschaftliche Fakultät Medizinische Fakultät | |||||||
| Dokument erstellt am: | 19.12.2024 | |||||||
| Dateien geändert am: | 19.12.2024 |
