Dokument: Clinical applications of fibroblast activation protein inhibitor positron emission tomography (FAPI-PET)
| Titel: | Clinical applications of fibroblast activation protein inhibitor positron emission tomography (FAPI-PET) | |||||||
| URL für Lesezeichen: | https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=67936 | |||||||
| URN (NBN): | urn:nbn:de:hbz:061-20241210-093554-6 | |||||||
| Kollektion: | Publikationen | |||||||
| Sprache: | Englisch | |||||||
| Dokumententyp: | Wissenschaftliche Texte » Artikel, Aufsatz | |||||||
| Medientyp: | Text | |||||||
| Autoren: | Mori, Yuriko [Autor] Novruzov, Emil [Autor] Schmitt, Dominik [Autor] Cardinale, Jens [Autor] Watabe, Tadashi [Autor] Choyke, Peter L. [Autor] Alavi, Abass [Autor] Haberkorn, Uwe [Autor] Giesel, Frederik L. [Autor] | |||||||
| Dateien: |
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| Beschreibung: | The discovery of fibroblast activation protein inhibitor positron emission tomography (FAPI-PET) has paved the way for a new class of PET tracers that target the tumor microenvironment (TME) rather than the tumor itself. Although 18F-fluorodeoxyglucose (FDG) is the most common PET tracer used in clinical imaging of cancer, multiple studies have now shown that the family of FAP ligands commonly outperform FDG in detecting cancers, especially those known to have lower uptake on FDG-PET. Moreover, FAPI-PET will have applications in benign fibrotic or inflammatory conditions. Thus, even while new FAPI-PET tracers are in development and applications are yet to enter clinical guidelines, a significant body of literature has emerged on FAPI-PET, suggesting it will have important clinical roles. This article summarizes the current state of clinical FAPI-PET imaging as well as potential uses as a theranostic agent. | |||||||
| Rechtliche Vermerke: | Originalveröffentlichung:
Mori, Y., Novruzov, E., Schmitt, D., Cardinale, J., Watabe, T., Choyke, P. L., Alavi, A., Haberkorn, U., & Giesel, F. L. (2024). Clinical applications of fibroblast activation protein inhibitor positron emission tomography (FAPI-PET). Njp Imaging, 2, Article 48. https://doi.org/10.1038/s44303-024-00053-z | |||||||
| Lizenz: |  Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz | |||||||
| Fachbereich / Einrichtung: | Medizinische Fakultät | |||||||
| Dokument erstellt am: | 10.12.2024 | |||||||
| Dateien geändert am: | 10.12.2024 |
