Dokument: The impact of ethnic background on ICU care and outcome in sepsis and septic shock – A retrospective multicenter analysis on 17,949 patients

Titel:The impact of ethnic background on ICU care and outcome in sepsis and septic shock – A retrospective multicenter analysis on 17,949 patients
URL für Lesezeichen:https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=67390
URN (NBN):urn:nbn:de:hbz:061-20241107-124225-9
Kollektion:Publikationen
Sprache:Deutsch
Dokumententyp:Wissenschaftliche Texte » Artikel, Aufsatz
Medientyp:Text
Autoren: Koköfer, Andreas [Autor]
Mamandipoor, Behrooz [Autor]
Flamm, Maria [Autor]
Rezar, Richard [Autor]
Wernly, Sarah [Autor]
Datz, Christian [Autor]
Jung, Christian [Autor]
Osmani, Venet [Autor]
Wernly, Bernhard [Autor]
Bruno, Raphael Romano [Autor]
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Dateien vom 07.11.2024 / geändert 07.11.2024
Stichwörter:Intensive care, Sepsis, Very old, Very elderly, Old, Octogenarian, Geriatric, Critically ill, Elderly
Beschreibung:Background

Previous studies have been inconclusive about racial disparities in sepsis. This study evaluated the impact of ethnic background on management and outcome in sepsis and septic shock.
Methods

This analysis included 17,146 patients suffering from sepsis and septic shock from the multicenter eICU Collaborative Research Database. Generalized estimated equation (GEE) population-averaged models were used to fit three sequential regression models for the binary primary outcome of hospital mortality.
Results

Non-Hispanic whites were the predominant group (n = 14,124), followed by African Americans (n = 1,852), Hispanics (n = 717), Asian Americans (n = 280), Native Americans (n = 146) and others (n = 830). Overall, the intensive care treatment and hospital mortality were similar between all ethnic groups. This finding was concordant in patients with septic shock and persisted after adjusting for patient-level variables (age, sex, mechanical ventilation, vasopressor use and comorbidities) and hospital variables (teaching hospital status, number of beds in the hospital).
Conclusion

We could not detect ethnic disparities in the management and outcomes of critically ill septic patients and patients suffering from septic shock. Disparate outcomes among critically ill septic patients of different ethnicities are a public health, rather than a critical care challenge.
Rechtliche Vermerke:Originalveröffentlichung:
Koköfer, A., Mamandipoor, B., Flamm, M., Rezar, R., Wernly, S., Datz, C., Jung, C., Osmani, V., Wernly, B., & Bruno, R. R. (2023). The impact of ethnic background on ICU care and outcome in sepsis and septic shock – A retrospective multicenter analysis on 17,949 patients. BMC Infectious Diseases, 23, Article 194. https://doi.org/10.1186/s12879-023-08170-7
Lizenz:Creative Commons Lizenzvertrag
Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz
Fachbereich / Einrichtung:Medizinische Fakultät
Dokument erstellt am:07.11.2024
Dateien geändert am:07.11.2024
english
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