Dokument: Influence of benign prostatic hyperplasia patterns detected with MRI on the clinical outcome after prostatic artery embolization
| Titel: | Influence of benign prostatic hyperplasia patterns detected with MRI on the clinical outcome after prostatic artery embolization | |||||||
| URL für Lesezeichen: | https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=67383 | |||||||
| URN (NBN): | urn:nbn:de:hbz:061-20241107-103838-9 | |||||||
| Kollektion: | Publikationen | |||||||
| Sprache: | Englisch | |||||||
| Dokumententyp: | Wissenschaftliche Texte » Artikel, Aufsatz | |||||||
| Medientyp: | Text | |||||||
| Autoren: | Boschheidgen, Matthias [Autor] Al-Monajjed, Rouvier [Autor] Minko, Peter [Autor] Jannusch, Kai [Autor] Ullrich, Tim [Autor] Radke, Karl Ludger [Autor] Michalski, René [Autor] Albers, Peter [Autor] Radtke, Jan Philipp [Autor] Antoch, Gerald [Autor] | |||||||
| Dateien: |
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| Stichwörter: | Prostatic arterial embolization, Prostate MRI, Hyperplasia patterns, Benign prostatic hyperplasia | |||||||
| Beschreibung: | Background
To investigate the influence of benign prostatic hyperplasia (BPH) patterns detected with MRI on clinical outcomes after prostatic artery embolization (PAE). Materials & methods This retrospective study included 71 consecutive patients with lower urinary tract symptoms (LUTS), who underwent magnetic resonance imaging (MRI) of the prostate followed by PAE at a single centre. MRI scans were evaluated and BPH patterns were determined according to Wasserman type and a modified BPH classification. Additionally, scans were evaluated regarding the presence of adenomatous-dominant benign prostatic hyperplasia (AdBPH). LUTS were assessed using the International Prostate Symptom Score (IPSS) and urinary flow rate (Qmax). Follow-up examination included MRI and clinical outcome. Results For clinical outcome at follow-up, IPSS showed median reduction of 54% (IQR 41—75%) and Qmax improved by 4.1 ml/s. We noted significant reduction in volume, intraprostatic protrusion, and prostatic urethral angle in our collective (p < 0.01). Median volume reduction was 25% (IQR 15%—34%). Bilateral embolization was a significant predictor for volume reduction at follow-up. Multiple linear regression analysis showed significant effect of high initial volume on reduction in IPSS after treatment (p < 0.01). Presence of AdBPH was significantly associated with both, volume loss and clinical improvement in terms of IPSS reduction (p < 0.01). Neither BPH pattern based on the Wassermann type nor modified BPH classification were significantly related with postinterventional IPSS and volume loss. Conclusions Men benefit from PAE regardless the macroscopic BPH MRI pattern. Preinterventional prostate volume and presence of AdBPH on MRI should be considered for outcome prognosis after PAE. | |||||||
| Rechtliche Vermerke: | Originalveröffentlichung:
Boschheidgen, M., Al-Monajjed, R., Minko, P., Jannusch, K., Ullrich, T., Radke, K. L., Michalski, R., Radtke, J. P., Albers, P., Antoch, G., & Schimmöller, L. (2023). Influence of benign prostatic hyperplasia patterns detected with MRI on the clinical outcome after prostatic artery embolization [OnlineRessource]. CVIR Endovascular, 6(1), Article 9. https://doi.org/10.1186/s42155-023-00357-y | |||||||
| Lizenz: |  Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz | |||||||
| Fachbereich / Einrichtung: | Medizinische Fakultät | |||||||
| Dokument erstellt am: | 07.11.2024 | |||||||
| Dateien geändert am: | 07.11.2024 |
