Dokument: Assessment of Laser Parameters to Improve Lid Tension—A Proof of Concept towards Lasercanthoplasty
| Titel: | Assessment of Laser Parameters to Improve Lid Tension—A Proof of Concept towards Lasercanthoplasty | |||||||
| URL für Lesezeichen: | https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=67001 | |||||||
| URN (NBN): | urn:nbn:de:hbz:061-20241010-111051-8 | |||||||
| Kollektion: | Publikationen | |||||||
| Sprache: | Englisch | |||||||
| Dokumententyp: | Wissenschaftliche Texte » Artikel, Aufsatz | |||||||
| Medientyp: | Text | |||||||
| Autoren: | Holtmann, Christoph [Autor] Witt, Joana [Autor] Schilcher, Alexandra [Autor] Avdakovic, Amar [Autor] Hutfilz, Alessa [Autor] Theisen-Kunde, Dirk [Autor] Wiebe-Ben Zakour, Katharina [Autor] Knop, Erich [Autor] Geerling, Gerd [Autor] | |||||||
| Dateien: |
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| Stichwörter: | laser treatment lid tensionbasic research, dry eye, ocular surface, meibomian gland dysfunction | |||||||
| Beschreibung: | Background: Preliminary clinical work indicates that increasing eyelid tension improves the function of the meibomian glands. The aim of this study was to optimize laser parameters for a minimally invasive laser treatment to increase eyelid tension by coagulation of the lateral tarsal plate and canthus.
Methods: Experiments were performed on a total of 24 porcine lower lids post mortem, with six lids in each group. Three groups were irradiated with an infrared B radiation laser. Laser-induced lower eyelid shortening was measured and the increase in eyelid tension was assessed with a force sensor. A histology was performed to evaluate coagulation size and laser-induced tissue damage. Results: In all three groups, a significant shortening of the eyelids after irradiation was noticed (p < 0.0001). The strongest effect was seen with 1940 nm/1 W/5 s, showing −15.1 ± 3.7% and −2.5 ± 0.6 mm lid shortening. The largest significant increase in eyelid tension was seen after placing the third coagulation. Conclusion: Laser coagulation leads to lower eyelid shortening and an increase in lower eyelid tension. The strongest effect with the least tissue damage was shown for laser parameters of 1470 nm/2.5 W/2 s. In vivo studies of this effect have to confirm the efficacy of this concept prior to clinical application. | |||||||
| Rechtliche Vermerke: | Originalveröffentlichung:
Holtmann, C., Witt, J., Schilcher, A., Avdakovic, A., Hutfilz, A., Theisen-Kunde, D., Wiebe-Ben Zakour, K., Knop, E., & Geerling, Gerd . (2023). Assessment of Laser Parameters to Improve Lid Tension—A Proof of Concept towards Lasercanthoplasty [OnlineRessource]. International Journal of Molecular Sciences, 24(5), Article 4757. https://doi.org/10.3390/ijms24054757 | |||||||
| Lizenz: |  Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz | |||||||
| Fachbereich / Einrichtung: | Medizinische Fakultät | |||||||
| Dokument erstellt am: | 10.10.2024 | |||||||
| Dateien geändert am: | 16.10.2024 |
