Dokument: Muskelgesundheit und Prähabilitation in der Kniegelenksendoprothetik: Einfluss der Blood-Flow-Restriction Trainingstherapie als prähabilitativer Ansatz im klinisch-randomisierten Studiensetting auf die postoperative Regeneration von Muskelmasse, -kraft und Funktionalität nach elektiver Kniegelenksendoprothetik
| Titel: | Muskelgesundheit und Prähabilitation in der Kniegelenksendoprothetik: Einfluss der Blood-Flow-Restriction Trainingstherapie als prähabilitativer Ansatz im klinisch-randomisierten Studiensetting auf die postoperative Regeneration von Muskelmasse, -kraft und Funktionalität nach elektiver Kniegelenksendoprothetik | |||||||
| Weiterer Titel: | Muscle health and prehabilitation in total knee arthroplasty: impact of blood-flow restriction exercise as a prehabilitation therapy in a clinical randomized trial setting on postoperative recovery of muscle mass, strength, and functionality after elective total knee arthroplasty | |||||||
| URL für Lesezeichen: | https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=62600 | |||||||
| URN (NBN): | urn:nbn:de:hbz:061-20230511-105537-3 | |||||||
| Kollektion: | Dissertationen | |||||||
| Sprache: | Deutsch | |||||||
| Dokumententyp: | Wissenschaftliche Abschlussarbeiten » Dissertation | |||||||
| Medientyp: | Text | |||||||
| Autor: | Franz, Alexander [Autor] | |||||||
| Dateien: |
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| Beitragende: | PD Dr. Bittersohl, Bernd [Gutachter] PD Dr. med. Zilkens, Christoph [Gutachter] | |||||||
| Stichwörter: | Okklusionstraining, Training, Muskulatur, Atrophie, Operation | |||||||
| Dewey Dezimal-Klassifikation: | 600 Technik, Medizin, angewandte Wissenschaften » 610 Medizin und Gesundheit | |||||||
| Beschreibungen: | Die endoprothetische Versorgung des Kniegelenks (engl. Total-Knee-Arthroplasty, TKA) ist eine der erfolgreichsten Eingriffe bei Gonarthrose zur Verbesserung der Mobilität und Minderung chronischer Schmerzen. Allerdings führt die Operation zu langanhaltenden muskulären Atrophien sowie Defiziten in der Muskelaktivierung und Kraftgenerierung. Ein neuer Ansatz zur Verbesserung des postoperativen klinischen Ergebnisses ist die Anwendung präoperativer Trainingsprogramme (Prähabilitation). In diesem Zusammenhang kristallisiert sich eine neue Trainingstechnik zunehmend heraus, die für Arthrose-betroffene Patienten einen schmerzfreien Weg zum Muskelaufbau generieren könnte, dass sog. Blood-Flow-Restriction Training (BFR).
Die vorliegende Dissertation bietet eine neue, empirisch-fundierte Analyse und Anwendung des BFR-Trainings als Prähabilitationskonzept vor der endoprothetischer Versorgung des Kniegelenks. Ausgehend von der Beschreibung der Muskelgesundheit der orthopädischen Patientenkohorte mit Gonarthrose, fokussiert die vorliegende Thesis die Genese der prä-, peri- und postoperativen Muskelatrophie, deren Einfluss auf die Rehabilitation und dessen Verbesserung durch eine präoperative Prähabilitationstherapie mit BFR-Training. Diese Dissertation umfasst insgesamt drei internationale Publikationen. Im Rahmen zweier Übersichtsarbeiten der aktuellen Literatur wurde zunächst die Patientenkohorte der orthopädischen Endoprothetik beschrieben und folgend die aktuellen Prähabilitationsansätze, deren Einfluss auf die postoperative Regeneration sowie die Hypothesenstellung der Einführung des BFR-Trainings thematisiert. Auf Basis dieser Erkenntnisse wurde eine klinisch-prospektive Studie konzipiert, bei der das BFR-Training als Prähabilitation vor einer elektiven TKA angewandt wurde. Die Ergebnisse ermöglichen eine erste Bewertung des Effektes einer BFR-Prähabilitation auf die prä- und postoperative Muskelgesundheit orthopädischer Patienten mit Gonarthrose.Total knee arthroplasty (TKA) is one of the most successful interventions for gonarthrosis to improve mobility and reduce chronic pain. However, the surgical procedure leads to long-lasting muscular atrophy and deficits in muscle activation and strength development. A new approach to improve postoperative clinical outcome is the use of preoperative exercise programs (prehabilitation). In this context, a new training technique is increasingly emerging that could generate a painless pathway to muscle gains for osteoarthritis-affected patients, the blood-flow restriction training (BFR). This dissertation provides a new, empirically based analysis and application of BFR-training as a prehabilitation concept prior to elective TKA. Based on the description of muscle health of the orthopedic patient cohort with gonarthrosis, this thesis analyzed the genesis of pre-, peri- and postoperative muscle atrophy, its influence on rehabilitation and its improvement by preoperative prehabilitation therapy with BFR-training. This dissertation includes a total of three international publications. In two reviews of the current literature, the muscle health of the orthopedic patient cohort which received a TKA and the current prehabilitation approaches are described. Furthermore, the impact of current prehabilitation protocols on postoperative regeneration as well as the hypothesis of the beneficial effects of BFR-training were addressed. Based on these findings, a clinical prospective study was designed, where BFR-Training was applied as prehabilitation technique in front of a TKA-surgery to investigate its impact on pre- and postoperative muscle health in orthopedic patients with gonarthrosis. | |||||||
| Quelle: | Literatur
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| Lizenz: |  Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz | |||||||
| Fachbereich / Einrichtung: | Medizinische Fakultät | |||||||
| Dokument erstellt am: | 11.05.2023 | |||||||
| Dateien geändert am: | 11.05.2023 | |||||||
| Promotionsantrag am: | 08.03.2018 | |||||||
| Datum der Promotion: | 09.03.2023 |
